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and Puerto Rico in a 1:1 ratio to receive maximum tolerated dose of Zepbound (10 mg or 15 mg) or Wegovy (1.7 mg or 2.4 mg)

This creates a sustained feeling of fullness after meals

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Thermogenesis Upregulation: Some peptides, particularly glucagon receptor agonists, increase brown adipose tissue (BAT) activity raising basal metabolic rate

with severe renal impairment

Heterogeneity was low: df = 21 (P 0.776), I2 = 0